Scrambler Therapy for the Treatment of Multiple System Atrophy-Parkinsonian Subtype Pain: A Case Report

Case Reports A A Pract 2022 Jan 18;16(1):e01560. doi: 10.1213/XAA.0000000000001560. PMID: 35050906

Scrambler Therapy for the Treatment of Multiple System Atrophy-Parkinsonian Subtype Pain: A Case Report

Eric J Wang  1 Lauren E Berninger  2   3 Alexander Y Pantelyat  4 Joann B Hunsberger  1 Thomas J Smith  5

  • 1 From the Department of Anesthesiology and Critical Care Medicine.
  • 2 Departments of Medicine.
  • 3 Oncology, Section of Palliative Medicine.
  • 4 Department of Neurology, Johns Hopkins Hospital, Baltimore, Maryland.
  • 5 Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland.

Abstract

The management of pain in patients with multiple system atrophy (MSA) is often inadequate, and treatments commonly result in adverse effects. A 63-year-old man with the parkinsonian subtype of MSA presented with bilateral neck, shoulder, upper extremity, lower extremity, and low back pain of 6 years’ duration. His baseline pain was 5 of 10 with flares to 10 of 10. After 4 35-minute scrambler therapy (ST) treatments, his pain was reduced to 0 of 10. His pain relief after 4 ST sessions lasted for 6 weeks. No complications or adverse effects occurred. ST deserves further study for patients with atypical parkinsonism.

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